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Rapamycin (Sirolimus)
Rapamycin (Sirolimus)
- 12 capsules/bottle
$83/mo
billed quarerly
$249/bottle, lasts 3 months
Rapamycin is considered to be one of the most promising healthspan-promoting therapies for its role in slowing down the formation of senescent cells through its inhibition of the mTOR complex I pathway.
Taken in small doses over an extended period of time, Rapamycin supports processes that preserve cellular health with age, leading to a longer period of life spent active and with less dysfunction.
Joi drugs may include compounded products that have not been approved by the FDA.The FDA does not verify the safety or effectiveness of compounded drugs including compounded Rapamycin (Sirolimus). Joi specialists may prescribe this medication off label from its intended use.Read More
Potential Benefits
Promote a longer and healthier lifespan
Improve metabolic health
Strengthen immune function
Help boost overall energy levels
Improve skin health
What's Included?
Board Certified Clinicians
Lifestyle & Nutrition Support
Unlimited Messaging
1:1 Coaching
Doctor Prescribed Medications
Access to Labs & Supplements
We're with you every step of the way.
Complete the online health history and consent forms
Fill out the online health history and consent forms or contact your coach if you are a current patient.
Lab Work
Complete a lab or share one you've done within the last 90 days.
Shipped to your door
A clinician will go over your health history and goals to ensure you are a candidate. If approved, your medication will be shipped to your door.
Ongoing Care
We will schedule a lab draw & follow-up visit after the 3rd month of treatment. After that, quarterly check-ins with annual lab draws.
Featured In
"A Trailblazing Leader in Health & Wellness"Read Article
We prescribe sirolimus because it is more bioavailable than the compounded version of rapamycin.
What is the rapamycin anti-aging protocol?
Generally, 5mg capsules taken once a week orally. New patients will be titrated up by clinician guidance. Providers may also cycle patients off for a short period of time.
Do I need labs to be on treatment?
We require a lab to start and then after 3 months of treatment. After that we test annually.
What are the side effects?
Possible side effects include sore or inflamed mouth, weakened immune system, anemia or fatigue, constipation or diarrhea, elevated lipid levels, high blood pressure, swollen hands or feet. Please contact us on the onset of any symptom you think may be related to treatment.
What is autophagy?
Rapamycin directly stimulates the cellular cleaning process known as autophagy, effectively clearing toxic debris and promoting cellular rejuvenation.
What is cellular senescence?
Cellular senescence is a process that results from a variety of stresses and leads to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases.
What is the mTOR pathway?
The mTOR pathway, found in all cells, determines when a cell should grow and divide. However, with time, it can become too active, resulting in unchecked cell growth and compromised tissue health. Rapamycin is a direct inhibitor of the mTOR pathway. Low doses of rapamycin appear to reset mTOR activity to a more youthful state—active when needed and dormant when not required.
Energy, mood, even sex drive – it all comes down to your hormones. The Complete Hormone lab panel provides a comprehensive examination of 45 key markers. You’ll get insights into why you may be functioning at a lower level than normal and where to go from there.
Recommended For:
Menopause Care
Sexual Health
Hormone + Metabolic + Thyroid
Balancing it all immediately goes out the window when your hormone and metabolic function is off. Gain strategic support (and balance) with Joi’s Advanced Hormone + Metabolic Health labs. We’ll help you evaluate any deficiencies in your blood that may be making you more susceptible to the challenges of modern living.
Recommended For:
Menopause Care
Sexual Health
Weight Loss
Thyroid
Comprehensive Panel
This test is a great one-stop shop for all of your essential functions. This 77 marker diagnostic lab panel not only gives us a clear picture of your overall health and wellness but drills down into the nitty gritty so we can customize a proactive plan for optimization both physically and mentally. These results will inform just how much room for growth there is in your wellbeing—and how you can get back up to feeling 100%.
Recommended For:
Menopause Care
Sexual Health
Weight Loss
Longevity
Heart
Stress
Vitamins & Minerals
Inflammation
At-home Hormone Kit
With one of the most comprehensive at-home hormone testing kits on the market, Joi will empower you on your journey to feeling your best. This test analyzes 11 key biomarkers essential for optimal health & wellbeing.
Zipcode Verification
This product is only available in certain zipcodes. Check your zipcode below to make sure that we can service your area.
Looks like you are in New York or New Jersey - due to local state requirements, we have different pricing in these two states. Please confirm your location if you are in NY or NJ or close this window to see pricing for the rest of the United States.
NY & NJ Residents
It looks like you are in New York or New Jersey - due to local requirements we have different lab diagnostics pricing in these states. Please close this message to review the revised applicable pricing for your service area.
Behavioral Health Resources
Thank you for choosing us to provide support with your health needs. We want to ensure our patients receive the most appropriate and evidence-based care when working with our team of medical professionals. Unfortunately, the behavioral health history that you have identified is not considered to be best practice when treated through telehealth. When individuals are experiencing conditions that you have identified, since patient safety is paramount, we refer them to a trusted local provider in their immediate area for in-person care for the most beneficial results.
We apologize for any inconvenience this may cause and fully appreciate the opportunity that you have provided us in choosing our service for your care. We have curated this list of resources to assist based on potential needs and/or concerns that were mentioned during your visit.
Crisis/Emergency Resources:
Phone Call:
988 - Crisis Support Lifeline
1-800-273-8255 - National Crisis Support
1-866-488-7386 or text START to 678678. A national 24-hour, toll free confidential suicide hotline for LGBTQ youth.
Text:
Text MHA to 741741 and you will be connected to a trained Crisis Counselor. Crisis Text Line provides free, text-based support 24/7.
Due to regulations beyond our control, we cannot ship testosterone therapy to your state. We can, however, still ship other hormone therapies, including estrogen, progesterone, DHEA, pregnanolone and all peptide therapy.
Restricted Product Notice
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