I lost 75 pounds in 6 months with Joi. I didn’t think there would ever be anything that worked. I was stuck in a cycle of yo-yo dieting and then punishing myself for failing. I finally feel like there’s something that works for me that’s effective, sustainable, and just easy. I feel incredible!
Learn MoreTrouble losing weight? Joi can help.
Lose up to 15% of your body weight and keep it off. We pair clinically proven GLP-1 medications with 1:1 lifestyle coaching to help make your weight loss goals a reality.
Complete the online health history and consent forms.
Start by completing the online health history and consent forms.
Meet your coach.
A patient coordinator will call you to set up your labwork (if needed) and your virtual appointment with a provider or coach.
Personalized Treatments Shipped Right to Your Door
Go over symptoms and goals during your visit and get customized prescription therapies shipped right to your door.

Your Current Weight
After Treatment
GLP-1 trial results showed overweight or obese adults receiving weekly peptide therapy had a mean weight loss of 14.9% at 68 weeks.
Learn More
The impact of weight loss and healthy weight maintenance extends beyond just improving your appearance and waistline. Chronic medical conditions including hypertension, diabetes, high cholesterol, and hormonal declines or fluctuations can all be impacted by being overweight. Whatever your goals, there is a treatment plan for you. At Joi, our weight loss programs are customized and designed for your desired outcome and weight wellness.
Melissa Loseke, DO PhD
Medical Advisor

That’s what we are here for! Let’s talk and determine which pathway we will go down together. Either way, we are here to help you reach your health and wellness goals.
No, not at this time. You can, however, use your HSA/FSA card to pay for treatment.
Semaglutide is a glucagon-like peptide (GLP-1) analog. GLP-1 is a hormone naturally produced in the small intestine that stimulates insulin secretion and inhibits glucagon secretion, thereby lowering blood sugar.
Studies show that semaglutide reduces appetite, improves control of eating, and reduces food cravings in addition to improving glycemic control. Glucagon-like peptide-1 (GLP-1) incretin hormone that helps the pancreas release insulin, which in turn helps the body control blood sugar levels.
Tirzepatide combines two classes of medications: GLP-1 and GIP whereas Semaglutide is just the GLP-1. In some studies, Tirzepatide was found to be superior in treating diabetes patients to Semaglutide. It works by mimicking the effects of incretin hormones–or, hormones that are released after eating that regulate the amount of insulin your pancreas secretes and lowers the amount of glucose your liver makes. In short, this helps you to feel fuller longer, slow down digestion, and lowers your blood sugar.
Tirzepatide combines two classes of medications: GLP-1 and GIP, whereas semaglutide includes just the GLP-1. Patients are reporting significantly less nausea symptoms with tirzpeatide.
You will start on a lower dose and then titrate up every 4 weeks. It’s important to let your body get used to the medication before upping your dose. Many people will feel less hunger and reduced cravings within the first 24-48 hours. The best method for losing weight is slow and steady. It’s important to focus on upgrading your lifestyle habits to complement with the medication.
Possible side effects of Semaglutide:
- Diarrhea
- Constipation
- Headaches
- Nausea
- Bloating
- Heartburn
- Stomach discomfort
- Fullness
Possible side effects of Tirzepatide:
- Difficulty in breathing or swallowing
- fast heartbeat
- gaseous stomach pain
- heartburn
- recurrent fever
- skin itching, rash, or redness
- stomach fullness
- swelling of the face, throat, or tongue
- vomiting
- yellow eyes or skin
- constipation
- diarrhea
Due to the beneficial lifestyle changes Semeaglutide and Tirzepatide promotes, it is possible to stay at a consistent weight when you get off of the medication. However, if you go back to poor eating and lifestyle habits, it is likely that weight gain will occur.
To experience the best results possible we recommend incorporating healthier eating habits and moving your body. Prioritizing protein, healthy fats and fiber as well as reducing the amount of processed foods is highly recommended.
GLP-1 medications are not included but your Care Team will work with you to get your medication covered by insurance. If insurance covers your medication, you may still be responsible for a copay.