[{"reviewer_name":"Kelsey Heenan","review_text":"\"Not only did I see my biomarkers improve, I know I\u2019m taking exactly what my body needs for better performance and better day to day life.\"","reviewer_image":"https:\/\/choosejoi.co\/wp-content\/uploads\/2024\/03\/Kelsey-H-headshot-1-e1711499030467.jpg"},{"reviewer_name":"Janna Breslin","review_text":"\"I need to be in tune with my body and Joi offers deep dive blood diagnostic labs that allow me to supplement with precision through Smart Supps.\"","reviewer_image":"https:\/\/choosejoi.co\/wp-content\/uploads\/2024\/03\/Screenshot-2024-03-26-172513.png"},{"reviewer_name":"Jessica Cooper","review_text":"\"The process with Joi was super easy and customized to fit my needs. I\u2019m busy with 3 kids, a husband and a full-time job so feeling my best and having energy is a must for me!\"","reviewer_image":"https:\/\/choosejoi.co\/wp-content\/uploads\/2024\/03\/jessica.jpg"}]
Rapamycin
Rapamycin
- 12 capsules/bottle
Rapamycin is considered to be one of the most promising healthspan-promoting therapies for its role in slowing down the formation of senescent cells through its inhibition of the mTOR complex I pathway.
Taken in small doses over an extended period of time, Rapamycin supports processes that preserve cellular health with age, leading to a longer period of life spent active and with less dysfunction.
Choose a lab to get started:
Benefits
Promote a longer and healthier lifespan
Delay the onset of age-related diseases
Improve metabolic health
Strengthen immune function
Help boost overall energy levels
Improve skin health
What's Included?
Board Certified Clinicians
Lifestyle & Nutrition Support
Unlimited Messaging
1:1 Coaching
Doctor Prescribed Medications
Access to Labs & Supplements
FAQs
What is sirolimus?
We prescribe sirolimus because it is more bioavailable than the compounded version of rapamycin.
What is the rapamycin anti-aging protocol?
Generally, 5mg capsules taken once a week orally. New patients will be titrated up by clinician guidance. Providers may also cycle patients off for a short period of time.
Do I need labs to be on treatment?
We require a lab to start and then after 3 months of treatment. After that we test annually.
What are the side effects?
Possible side effects include sore or inflamed mouth, weakened immune system, anemia or fatigue, constipation or diarrhea, elevated lipid levels, high blood pressure, swollen hands or feet. Please contact us on the onset of any symptom you think may be related to treatment.
What is autophagy?
Rapamycin directly stimulates the cellular cleaning process known as autophagy, effectively clearing toxic debris and promoting cellular rejuvenation.
What is cellular senescence?
Cellular senescence is a process that results from a variety of stresses and leads to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases.
What is the mTOR pathway?
The mTOR pathway, found in all cells, determines when a cell should grow and divide. However, with time, it can become too active, resulting in unchecked cell growth and compromised tissue health. Rapamycin is a direct inhibitor of the mTOR pathway. Low doses of rapamycin appear to reset mTOR activity to a more youthful state—active when needed and dormant when not required.
The process with Joi was super easy. I just signed up online and did all my visits virtually. They customized solutions that fit my needs. I’m busy with 3...
I’ve had an amazing experience with Joi and the peptide therapy! After injuring my shoulder during my last prep, I started using peptides to reduce inflammation and speed up...
Everyone on this team is absolutely amazing and so delightful to work with. Dr.Folkers and Lauren are always there to make sure all my questions are answered. Been on...
The process with Joi was super easy. I just signed up online and did all my visits virtually. They customized solutions that fit my needs. I’m busy with 3 kids, a husband and a full-time job so feeling my best and having energy is a must for me!
Amber Flannigan Review
I’ve had an amazing experience with Joi and the peptide therapy! After injuring my shoulder during my last prep, I started using peptides to reduce inflammation and speed up the healing process. This has really helped with my recovery time. What I am most amazed by is how the use of peptides has allowed me to maintain my muscle mass, even when I wasn’t able to push as hard in the gym. Now I am hitting PRs and am seeing even more positive changes in my strength and physique, which is so rewarding!
Danielle Henrickson Review
Everyone on this team is absolutely amazing and so delightful to work with. Dr.Folkers and Lauren are always there to make sure all my questions are answered. Been on semaglutide for about 9 weeks and I’m down 9 lbs since starting it. Highly recommend this company for all peptide / hormone needs. You won’t find a company that does it better.
Robyn Petasne Review
I was so happy to discover JOI. I have lost 17 lbs! I havent lost that much at one time since I started menopause and its only been 3 months (and 3 vacations!) But more importantly…Using the peptide has freed me from constant food obsessions without side effects. This is really BIG for me. NP Lauren was terriffic and I love the telemed. Its a huge time saver and makes it so easy. The entire staff has been super supportive teaching me how to give myself the injections, its simple and painless. Im also taking 2 other peptides, one for joint pain and one for stomach/GERD issues and it was a lifesaver to me. I started it just a week before I went to France on vacation and had no stomach issues, even drinking coffee! Im really grateful to JOI, having a more natural and safe way to handle my health issues gives me more piece of mind then popping artificial pills. Thank you
Abbie Wood Review
I can’t say enough great things about Joi. I have been tossing around the idea of starting on some peptides for a few months now and it was one of the best decisions I have made. The peptides have given me so much energy, confidence, focus/drive, and incredible sleep. My kids even notice a difference in my energy! Signing up with Joi was seriously as easy as 1,2,3 from the comfort of my own home. I signed up online, had my initial consultation via video call to answer all my questions and concerns, and then my product arrived just a few days later! I had another video call to go through how to administer the peptides and that was it! I would highly recommend Joi!
